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WSO may stand for:

  • Waltham Symphony Orchestra in Waltham, Massachusetts, United States
  • Washabo Airport (IATA airport code) in Washabo, Suriname
  • Weapon Systems Officer (or weapon systems operator), a flight officer in the U.S. Air Force, Navy and Marine Corps, and in the British Royal Air Force
  • Wheeling Symphony Orchestra in Wheeling, West Virginia, United States
  • Wichita Symphony Orchestra in Wichita, Kansas, United States
  • Winnipeg Symphony Orchestra in Winnipeg, Manitoba, Canada
  • World Safety Organization, an international professional association in safety
  • World Sikh Organization, a non-profit organization
  • White superficial onychomycosis, a fungal infection of the nail plate