What is "nonsteroidal"

a. (context steroid English) That does not consist of, or contain steroids.

adj. not steroidal or not having the effects of steroid hormones [ant: steroidal]

n. an organic compound that does no contain a steroid [syn: nonsteroid]

Nonsteroidal is a term used to describe a compound that is not a steroid and to indicate as such.

It is used in the name of nonsteroidal anti-inflammatory drugs (NSAIDs) to distinguish them from corticosteroids as a class of anti-inflammatory agents.

Nonsteroidal is also used to describe steroidergic drugs that are not steroid derivatives. Examples include the following:

• Estrogens: benzestrol, bifluranol, DBE, diethylstilbestrol (stilbestrol), dienestrol, fosfestrol, hexestrol (dihydroxystilbestrol), methallenestril, methestrol, methestrol dipropionate, paroxypropione, prinaberel, and triphenylethylene, as well as many xenoestrogens
• SERMs: acolbifene, afimoxifene, arzoxifene, bazedoxifene, broparestrol, chlorotrianisene, clomifene, clomifenoxide, cyclofenil, droloxifene, enclomifene, endoxifen, ethamoxytriphetol, fispemifene, idoxifene, lasofoxifene, levormeloxifene, miproxifene, nafoxidine, nitromifene, ormeloxifene, ospemifene, panomifene, pipendoxifene, raloxifene, sivifene, tamoxifen, tesmilifene, toremifene, trioxifene, zindoxifene, zuclomifene
• Antiandrogens: apalutamide, bicalutamide, cimetidine, darolutamide, DIMP, enzalutamide, EPI-001, EPI-506, flutamide, hydroxyflutamide, inocoterone, ketoconazole, nilutamide, orteronel, RU-58642, RU-58841, and topilutamide
• SARMs: AC-262,356, acetothiolutamide, andarine, BMS-564,929, enobosarm (ostarine), GW-501516, JNJ-28330835, LGD-2226, LGD-3303, LGD-4033, S-23, and S-40503
• Miscellaneous: tanaproget ( progestogen), finerenone ( antimineralocorticoid), esaxerenone (antimineralocorticoid), apararenone (antimineralocorticoid), AZD5423 ( glucocorticoid), AL082D06 ( antiglucocorticoid), mapracorat ( SGRM), and Org 214007-0 (SGRM)