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Wiktionary
neurotoxin

n. (context neuroscience toxicology English) A toxin that specifically acts upon neurons, their synapses, or the nervous system in its entirety.

WordNet
neurotoxin

n. any toxin that affects neural tissues [syn: neurolysin]

Wikipedia
Neurotoxin

Neurotoxins are toxins that are poisonous or destructive to nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological insults that can adversely affect function in both developing and mature nervous tissue. The term can also be used to classify endogenous compounds, which, when abnormally contact , can prove neurologically toxic. Though neurotoxins are often neurologically destructive, their ability to specifically target neural components is important in the study of nervous systems. Common examples of neurotoxins include lead, ethanol (drinking alcohol), manganese glutamate, nitric oxide (NO), botulinum toxin (e.g. Botox), tetanus toxin, and tetrodotoxin. Some substances such as nitric oxide and glutamate are in fact essential for proper function of the body and only exert neurotoxic effects at excessive concentrations.

Neurotoxins inhibit neuron control over ion concentrations across the cell membrane, or communication between neurons across a synapse. Local pathology of neurotoxin exposure often includes neuron excitotoxicity or apoptosis but can also include glial cell damage. Macroscopic manifestations of neurotoxin exposure can include widespread central nervous system damage such as intellectual disability, persistent memory impairments, epilepsy, and dementia. Additionally, neurotoxin-mediated peripheral nervous system damage such as neuropathy or myopathy is common. Support has been shown for a number of treatments aimed at attenuating neurotoxin-mediated injury, such as antioxidant and antitoxin administration.

Usage examples of "neurotoxin".

Totuus was found in his system, but the NYU neurologists believe he had another compound in his bloodstream that combined with the Totuus to form a neurotoxin specific to the Broca area.

The neurotoxin venom is pumped in with one contraction of the muscular tail, and the titanothere topples to the ground with a crash, shaking the forest.

When he handled the various weapons, Fairhaven absorbed quite a cocktail of poisons through his skin: neurotoxins and other fast-acting systemics, no doubt.

Neurotoxins basically cause the roach to twitch itself to death, in the course of which it will frequently kick over on its back, there to flail helplessly until the end comes.

He'd been a young lieutenant at Dugway Proving Grounds when they'd had the well-publicized accident with GB, a persistent nerve agent that had blown too far and slaughtered a few hundred sheep-and neurotoxins were not a pretty death, even for sheep.

For the original strains of the bug had a novel property: they were a treasure house of neurotoxins.