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The Collaborative International Dictionary
Inoculation

Inoculation \In*oc"u*la"tion\, n. [L. inoculatio: cf. F. inoculation.]

  1. The act or art of inoculating trees or plants.

  2. (Med.) The act or practice of communicating a disease to a person in health, by inserting contagious matter in his skin or flesh, usually for the purpose of inducing immunity to the disease.

    Note: The use was formerly limited to the intentional communication of the smallpox, but is now extended to include any similar introduction of modified virus; as, the inoculation of rabies by Pasteur. The organisms inoculated are usually an attentuated form of the disease-causing organism, which may multiply harmlessly in the body of the host, but induce immunity to the more virulent forms of the organism.

  3. Fig.: The communication of principles, especially false principles, to the mind.

  4. (Microbiology) The introduction of microorganisms into a growth medium, to cause the growth and multiplication of the microorganisms.

Douglas Harper's Etymology Dictionary
inoculation

mid-15c. in horticulture; 1714 in pathology, from Latin inoculationem (nominative inoculatio) "an engrafting, budding," noun of action from past participle stem of inoculare (see inoculate).

Wiktionary
inoculation

n. 1 (context immunology English) The introduction of an antigenic substance or vaccine into the body to produce immunity to a specific disease. 2 (context microbiology English) The introduction of a microorganism into a culture medium. 3 An inoculum, what is inoculated

WordNet
inoculation

n. taking a vaccine as a precaution against contracting a disease [syn: vaccination]

Wikipedia
Inoculation

Inoculation (also known as variolation) is a historical method for the prevention of smallpox by deliberate introduction of material from smallpox pustules into the skin. This generally produced a less severe infection than naturally-acquired smallpox, but still induced immunity to it. The term entered medical English through horticultural usage meaning to graft a bud (or eye) from one plant into another. It is derived from the Latin in + oculus (eye). Though innoculation/innoculate is sometimes seen, this is incorrect, possibly erroneously thought to be related to innocuous, which is derived from the Latin in + nocuus (not harmful).

The terms inoculation, vaccination, immunization and injection are often used synonymously to refer to artificial induction of immunity against various infectious diseases. This is supported by some dictionaries. However, there are some important historical and current differences. In English medicine inoculation referred only to the prevention of smallpox until the very early 1800s. When Edward Jenner introduced smallpox vaccine in 1798 this was initially called cowpox inoculation or vaccine inoculation. Soon, to avoid confusion, smallpox inoculation was referred to as variolation (from variola = smallpox) and cowpox inoculation was referred to as vaccination (from Jenner's use of Variolae vaccinae = smallpox of the cow). Then, in 1891 Louis Pasteur proposed that the terms vaccine/vaccination should be extended to include the new protective procedures being developed. Immunization refers to the use of all vaccines but also extends to the use of antitoxin, which contains preformed antibody to e.g. diphtheria or tetanus exotoxins. Inoculation is now more or less synonymous in nontechnical usage with injection etc., and the question e.g. 'Have you had your flu injection/vaccination/inoculation/immunization?' should not cause confusion. The focus is on what is being given and why, not the literal meaning of the technique used.

Inoculation also has a specific meaning for procedures done in vitro. These include the transfer of microorganisms into and from laboratory apparatus such as test tubes and petri dishes in research and diagnostic laboratories, and also in commercial applications such as brewing, baking and the production of antibiotics.

In almost all cases the material inoculated is called the inoculum, or less commonly the inoculant, although the term culture is also used for work done in vitro.

Usage examples of "inoculation".

However, there are good reasons for believing that with the introduction of hardy varieties and through the use of Northern grown seed, an inoculated soil, where inoculation may be necessary, that medium red clover will yet be grown over wide areas in all the provinces of Northwestern Canada, south of and including the Saskatchewan valley.

There was no inoculation to protect her from that or from someone seeing her come through and deciding she was a witch.

Ahrens had suddenly decided Kivrin needed another inoculation or if Dunworthy had raced off to the History Faculty and gotten them to change the rating back to a ten.

She remembered suddenly that her plague inoculation had itched and made a lump under her arm, but Dr.

Gilchrist was in the little waiting room, hale and hearty, wearing an NHS face mask, rolling up his sleeve in preparation for the inoculation a nurse was holding.

It took two weeks for the inoculation to confer full immunity, and seven days before partial.

It was a more severe inoculation than any man would ever get in nature.

The process of introducing them is generally referred to as a process of inoculation, and soils when treated successfully are said to be inoculated.

Because of this, inoculation can only, or at least chiefly, be effected through the use of soils on which that particular class of legumes have grown, or which are possessed of bacteria proper to that particular species.

The relation between abundant manuring and soil inoculation is worthy of more careful study, in the judgment of the author, than has yet been accorded to it.

Overflowing with energy and goodwill, he was ardent for reform of all kinds: smallpox inoculation for the poor, humane care for the insane, reform of the penal code, but especially for the abolition of slavery.

It was there, in Boston, that smallpox inoculation had been introduced in America more than half a century earlier, and by a kinsman of Adams, Dr.

Abigail came word that she and the children, having survived the long ordeal of inoculation in Boston, were at last home again in Braintree.

I have taken the liberty of consulting with Kes and creating an inoculation which should neutralize any gas used against you or Lieutenant Torres.

The Justice Department will be issuing indictments soon for crimes ranging from bringing a wild animal into the country without meeting the proper quarantine and inoculation requirements to endangering an endangered species.