Crossword clues for estradiol
Wiktionary
n. (context biochemistry English) A potent estrogenic hormone (''(17)-estra-1,3,5-triene-3,17-diol'') produced in the ovary of all vertebrates; the synthetic compound is used medicinally to treat estrogen deficiency and breast cancer.
WordNet
n. the most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer [syn: oestradiol]
Wikipedia
Estradiol, or more precisely, 17β-estradiol, is a steroid and estrogen sex hormone, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.
Estradiol or oestradiol ( American or British English usages), derives from estra-, Gk. (oistros, literally meaning "verve or inspiration") and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.
Estradiol is produced especially within the follicles of the female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principal pathway then converts progesterone to its 17-hydroxy derivative, 17-Hydroxyprogesterone, and then to Δ-androstenedione via sequential cytochrome P450-catalyzed oxidations. Action of aromatase on Δ-androstenedione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol. Alternatively, Δ-androstenedione can be converted into the androgen, testosterone, which in turn can be converted directly into 17β-estradiol.
Usage examples of "estradiol".
Short-chain aliphatic compounds are elaborated by female monkeys in response to estradiol, and these are of consuming interest to the males.
Most of the estrone and estradiol the body produces is quickly converted to estriol, but just to keep things interesting, some estriol can be produced from DHEA or androstenedione without involving estrone or estradiol at all!
Produced from cholesterol by way of pregnenolone, DHEA is an androgen that is metabolized to form androstenedione, which begets testosterone which begets estradiol and then estrone, and finally, estriol.
The results of many studies in laboratory animals and cell cultures have confirmed that estrone, equilin, estradiol, and ethinyl estradiol can all cause cancer in endometrial and breast tissue.
It is thought, for example, that phytoestrogens may block access to estrogen receptors by such procarcinogenic estrogens as estradiol.
Estrone acts as an antiestrogen, stopping the full action of estradiol.
Gillian watched the burnp and grind of the machines measuring out the active ingredients: levonorgestrel and ethinyl estradiol.
Because ethinyl estradiol is not metabolized in the liver the way natural estradiol is, it hangs around in the body far longer.
The results of many studies in laboratory animals and cell cultures have confirmed that estrone, equilin, estradiol, and ethinyl estradiol can all cause cancer in endometrial and breast tissue.
For women in perimenopause, or just prior to menopause, the declining levels of the hormone estradiol may increase your chance of poor sleep.
The conjugated estrogens, the Premarin, the estradiol, the ethinyl estradi-ol, they've all found their way into Seth's diet cola.