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entheogen

n. A psychoactive substance used for the purpose of inducing a mystical or spiritual experience.

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Entheogen

An entheogen ("generating the divine within") is any chemical substance used in a religious, shamanic, or spiritual context that often induces psychological or physiological changes.

Entheogens have been used to supplement many diverse practices geared towards achieving transcendence, including meditation, yoga, prayer, psychedelic art, chanting, and multiple forms of music. They have also been historically employed in traditional medicine via psychedelic therapy.

Entheogens have been used in a ritualized context for thousands of years; their religious significance is well established in anthropological and modern contexts. Examples of traditional entheogens include traditional psychedelics like peyote, psilocybin mushrooms, and ayahuasca, psychedelic- dissociatives like Tabernanthe iboga, atypical psychedelics like Salvia divinorum, quasi-psychedelics like cannabis, and deliriants like Amanita muscaria. Traditionally a tea, admixture, or potion like bhang is the preferred mode of ingestion.

With the advent of organic chemistry, there now exist many synthetic drugs with similar psychoactive properties, many derived from the aforementioned plants. Many pure active compounds with psychoactive properties have been isolated from these respective organisms and chemically synthesized, including mescaline, psilocybin, DMT, salvinorin A, ibogaine, ergine, and muscimol. Semi-synthetic (e.g., LSD used by the Neo-American Church) and synthetic drugs (e.g., DPT used by the Temple of the True Inner Light and 2C-B used by the Sangoma) have also been developed. Cannabis is the world's most widely used psychedelic drug, though it is more accurately referred to as a quasi-psychedelic drug, since its effect profile lacks the hallucinogenic and cognitive effects of traditional psychedelics.

More broadly, the term entheogen is used to refer to any psychoactive drugs when used for their religious or spiritual effects, whether or not in a formal religious or traditional structure. This terminology is often chosen to contrast with recreational use of the same drugs. Studies such as Timothy Leary's Marsh Chapel Experiment and Roland Griffiths' psilocybin studies at Johns Hopkins have documented reports of mystical/spiritual/religious experiences from participants who were administered psychoactive drugs in controlled trials. Ongoing research is limited due to widespread drug prohibition; however, some countries have legislation that allows for traditional entheogen use.