Crossword clues for potency
potency
Longman Dictionary of Contemporary English
The Collaborative International Dictionary
Potency \Po"ten*cy\, n. [L. potentia, from potens, -entis,
potent. See Potent, and cf. Potance, Potence,
Puissance.]
The quality or state of being potent; physical or moral
power; inherent strength; energy; ability to effect a
purpose; capability; efficacy; influence. ``Drugs of
potency.''
--Hawthorne.
A place of potency and away o' the state.
--Shak.
Douglas Harper's Etymology Dictionary
mid-15c., from Latin potentia "power," from potentem "potent" (see potent).
Wiktionary
n. 1 strength 2 power 3 The ability or capacity to perform something.
WordNet
n. capacity to produce strong physiological or chemical effects; "the toxin's potency"; "the strength of the drinks" [syn: effectiveness, strength]
the inherent capacity for coming into being [syn: potential, potentiality]
the state of being potent; a male's capacity to have sexual intercourse
Wikipedia
Potency may refer to:
- Potency (pharmacology), a measure of the activity of a drug in a biological system
- Virility
- Potency (stem cell) is a measure of the differentiation potential of stem cells
- Cell potency
- In homeopathic dilutions, potency is a measure of how dilute a substance is
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity. A highly potent drug (e.g., fentanyl, alprazolam, risperidone) evokes a given response at low concentrations, while a drug of lower potency ( codeine, diazepam, ziprasidone) evokes the same response only at higher concentrations. The potency depends on both the affinity and efficacy.
Affinity is the ability of the drug to bind to a receptor. Efficacy is the relationship between receptor occupancy and the ability to initiate a response at the molecular, cellular, tissue or system level. The response is equal to the effect, or (E), and depends on both the drug binding and the drug-bound receptor then producing a response; thus, potency depends on both affinity and efficacy. The agonist, the ligand, drug or hormone that binds to the receptor and initiates the response is usually abbreviated A or D. Below a certain concentration of agonist ([A]), E is too low to measure but at higher concentrations it becomes appreciable and rises with increasing agonist concentration [A] until at sufficiently high concentrations it can no longer be increased by raising [A] and asymptotes to a maximum E.
The E is the maximum possible effect for the agonist. The concentration of A at which E is 50% of E is termed the half maximal effective concentration and is abbreviated' [A]', or more commonly EC. The term "potency" refers to the [A] value. The lower the [A], the less the concentration of a drug is required to produce 50% of maximum effect and the higher the potency.
Higher potency does not necessarily mean more side effects.
The pharmacophore is the part of the drug molecule - the atoms and groups - that bind to the receptor; the "auxophore" are the parts of the molecule that are not directly involved in binding, but may rather interfere with binding, be essential for the arrangement of pharmacophoric elements, or may be irrelevant.
Usage examples of "potency".
However, while one focuses the attention on an unchanging object, there is the possibility of dementia setting in if one allows the potency of attentional vividness to wane.
Call Thou to mind the bounty which I bestowed upon Thee when I conversed with Thee in the midmost heart of My Sanctuary and aided Thee through the potency of the Holy Spirit that Thou mightest, as the peerless Mouthpiece of God, proclaim unto men the commandments of God which lie enshrined within the divine Spirit.
Merry stocks her shelves with sprays, toxins, and molecules of fearsome potency, all of them synthesized by evil alchemists and guaranteed to necrose Planet Earth for eternity.
This event impressed the populace, who supposed the accident to be due to an overdaring exercise of the divine potency.
Since vampire blood was supposed to temporarily relieve symptoms of illness and increase sexual potency, kind of like prednisone and Viagra rolled into one, there was a huge black market for genuine, undiluted vampire blood.
I have had some experience with the psychotomimetic drugs and was well aware of their potency.
Touched to tears by the unnamed loss that raged through him, he trembled, his emotion resharpened to unblunted potency, and his grief, too poignant to bear.
The stasis field held the shoppe inviolate, but though he was safe from the Infinite Dark Mass that pressed against its walls, its potency could still be felt: pressing against the field, incredible devouring power exerting unceasing pressure.
But by now the stims, adrenalin-activated, had released their full potency, and Ryne was a wild man.
Princess and Kedrigern supervised his treatment, swabbing his face with healing waters at sunrise and sunset and applying a theriacal salve of great potency four times a day.
Only in the bizarro world of Hollywood can such a harmless little chap as George exude massive sexual potency.
Silva Copperleaf by name, whose charms were of such a strength that their potency lasted not just from year to year, but continued to protect the folk who possessed them for generations.
Amphetamines are broken down chemically into three types: salts of racemic amphetamines, dextroamphetamines, and methamphetamines, which only differ in potencies.
Speed usually sells for about 10 to 25 cents a pill depending on potency, or in nickel bags and spoons of methedrine which comes in a tiny wax paper envelope.
Yet this is given only at the quadrillionth, or fourth degree of potency, and various substances are frequently administered at the decillionth or tenth degree, and occasionally at still higher attenuations with professed medicinal results.