Wikipedia
Panicudine (6-hydroxy-11-deoxy-13-dehydrohetisane) is a C- diterpene alkaloid of the hetisine type, first isolated from Aconitum paniculatum. It has empirical formula CHNO and a melting point of 249-250 °C. The structure was determined to be a hetisine type diterpene by noting infrared spectrum absorption bands of 3405 cm (OH), 1718 (C=O), and 1650 (C=C), a proton magnetic resonance spectrum with "secondary hydroxy (4.02 ppm, m, 1H, W = 10 Hz), exomethylene (4.87 and 4.76 ppm, br.s, 1H each), and tertiary methyl (1.29 ppm, s, 3H) groups and the absence of N-methyl, N- ethyl, and methoxy groups." Additional ultraviolet spectrum and carbon-13 NMR data, confirmed by high resolution mass spectrometry, completed the determination of the structure.
Panicudine was identified as an active antimicrobial substance in the chloroform extract of Polygonum aviculare, a traditional herbal medicine of the Mediterranean coastal region. It has also been isolated from epigeal parts of Rumex pictus. A variety of related alkaloids have been isolated from other natural sources.