Wiktionary
n. (context idiomatic English) Someone or something which is annoying, irritating or inconvenient
WordNet
n. a bothersome annoying person; "that kid is a terrible pain" [syn: pain, nuisance]
something or someone that causes trouble; a source of unhappiness; "washing dishes was a nuisance before we got a dish washer"; "a bit of a bother"; "he's not a friend, he's an infliction" [syn: annoyance, bother, botheration, pain, infliction, pain in the ass]
Usage examples of "pain in the neck".
In his youth he had been without direction, reckless, too loud, a real pain in the neck.
It is, I imagine, a severe pain in the neck to quite a few governments in Irene's universe.
Either way, they'd be an opportunity and a monstrous pain in the neck at one and the same time.