What is "levamisole"

n. (context organic compound English) A synthetic imidazothiazole derivative whose hydrochloride is used as an antibiotic.

Levamisole, marketed under the trade name Ergamisol, is a medication used to treat parasitic worm infections. It has also been studied as a method to stimulate the immune system as part of the treatment of cancer. Levamisole remains in veterinary use as a dewormer for livestock.

The most serious side effect of levamisole is low white blood cells that leaves person vulnerable to infection. It belongs to the class of synthetic imidazothiazole derivatives.

Levamisole was discovered in 1966 by Janssen Pharmaceutica. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It was withdrawn from the U.S. and Canadian markets in 1999 and 2003, respectively, due to the risk of side effects and the availability of more effective medications. The medication has been used as an adulterant in cocaine sold in the United States, Canada and United Kingdom, resulting in serious side effects.