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The Collaborative International Dictionary
Irreversibility

Irreversibility \Ir`re*vers`i*bil"i*ty\, n. The state or quality of being irreversible; irreversibleness.

Wiktionary
irreversibility

n. The quality of being irreversible; the lack of an ability to be reversed.

WordNet
irreversibility

n. the quality of being irreversible (once done it cannot be changed) [ant: reversibility]

Usage examples of "irreversibility".

Death is a cluster concept and requires several criteria in a lump, but irreversibility is the only absolute one.