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Longman Dictionary of Contemporary English
Hemoglobin F, or fetal hemoglobin, is composed of two alpha chains and two gamma chains. 214.
▪ Glycosylated hemoglobin refers to the specific red cell hemoglobin A types to which a glucose molecule becomes irreversibly attached.
▪ In contrast to hemoglobin F, most hemoglobins will denature in alkaline solution and precipitate upon the addition of ammonium sulfate.
▪ Iron deficiency anemia, as evidenced by a high prevalence of low hemoglobin levels, was a widespread problem.
▪ Over a period of time changes in hemoglobin and haematocrit levels of the patient are observed.
▪ The greater the glucose concentration in the plasma, the greater the number of hemoglobin molecules that will become glycosylated.
▪ This usually occurs when the drop in hemoglobin or blood volume is acute.
The Collaborative International Dictionary

Hemoglobin \Hem"o*glo"bin\, n. [Hemo- + globe.] (Physiol.) The normal coloring matter of the red blood corpuscles of vertebrate animals. It is composed of hematin and globulin, and is also called h[ae]matoglobulin. In arterial blood, it is always combined with oxygen, and is then called oxyhemoglobin. It crystallizes under different forms from different animals, and when crystallized, is called h[ae]matocrystallin. See Blood crystal, under Blood.

Douglas Harper's Etymology Dictionary

coloring matter in red blood stones, 1862, shortening of hæmatoglobin (1845), from Greek haimato-, comb. form of haima (genitive haimatos) "blood" (see -emia) + globulin, a type of simple protein, from globule, formerly a word for "corpuscle of blood."


n. The iron-containing substance in red blood cells that transports oxygen from the lungs to the rest of the body; it consists of a protein (''globulin''), and ''haem'' (a porphyrin ring with an atom of iron at its centre).


n. a hemoprotein composed of globin and heme that gives red blood cells their characteristic color; function primarily to transport oxygen from the lungs to the body tissues; "fish have simpler hemoglobin than mammals" [syn: haemoglobin, Hb]


Hemoglobin ; also spelledhaemoglobin and abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae) as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs ( lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism.

In mammals, the protein makes up about 96% of the red blood cells' dry content (by weight), and around 35% of the total content (including water). Hemoglobin has an oxygen-binding capacity of 1.34 mL O per gram, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood. The mammalian hemoglobin molecule can bind (carry) up to four oxygen molecules.

Hemoglobin is involved in the transport of other gases: It carries some of the body's respiratory carbon dioxide (about 20–25% of the total) as carbaminohemoglobin, in which CO is bound to the globin protein. The molecule also carries the important regulatory molecule nitric oxide bound to a globin protein thiol group, releasing it at the same time as oxygen.

Hemoglobin is also found outside red blood cells and their progenitor lines. Other cells that contain hemoglobin include the A9 dopaminergic neurons in the substantia nigra, macrophages, alveolar cells, and mesangial cells in the kidney. In these tissues, hemoglobin has a non-oxygen-carrying function as an antioxidant and a regulator of iron metabolism.

Hemoglobin and hemoglobin-like molecules are also found in many invertebrates, fungi, and plants. In these organisms, hemoglobins may carry oxygen, or they may act to transport and regulate other small molecules and ions such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. A variant of the molecule, called leghemoglobin, is used to scavenge oxygen away from anaerobic systems, such as the nitrogen-fixing nodules of leguminous plants, before the oxygen can poison (deactivate) the system.

Usage examples of "hemoglobin".

For example, one study of women undergoing gynecologic surgery indicated that the age of the patient had great diagnostic importance, and that notation of last menstrual period, biopsy of smear, pre-operative hemoglobin, and urine-sediment study were all much less important to making a diagnosis.

In us, the oxygen is carried to the tissues, and the carbon dioxide carried away by an iron compound, hemoglobin, but in many animals of Earth, the same function is performed by a copper compound, hemocyanin, which is an intense blue.

Hemoglobin, such as in our blood, and hemocyanin, like that in the blue blood of the Venerians, are practically unique in that respect.

The red blood corpuscles were drained of oxygen and now contained hemoglobin itself, not oxyhemoglobin, that bright red combination of hemoglobin and oxygen.

Behind her eyelids, she imagined her blood as a thick red river full of amoeba-like creatures: T cells, lymphocytes, phagocytes, doughnut-shaped hemoglobin, tumbling over and over, rushing past.

Is it intended to keep the hemoglobin from coagulating, or is it merely some kind of embellishment from art forms whose true origin has been lost to the mists of time?

Somehow, a small percentage of his blood cells have disintegrated, releasing hemoglobin.

Sexual reproduction and DNA, the patenting of hemoglobin and harnessing of oxygen as a higher-power energy source, all represented breakthroughs into new realms of capability, and eventually the development of the first functioning spacesuit in the form of the amphibian egg paved the way for migration into and colonizing of a completely new, initially hostile environment.

Emmy's, where the bone marrow is the primary target of the disease, namiloxiprine creates an unusual chemical environment in the marrow cavity and in the haversian canals, an environment that's extremely hostile to microorganisms but actually encourages the growth of marrow cells, the production of blood cells, and hemoglobin formation.

Hemoglobin prepared from what flows in my veins travels with normal Hemoglobin A when electrophoresed.

Conversely, if they set up a tuned Ledbetter projector and start running down or up the scale, when they come to your individual, unique frequency, your red blood cells start absorbing energy, the hemoglobins protein breaks down and -- Spung!

A vertebrate, of course, which checks to ten decimal places, mitotic spindle, mitochondria all quite ordinary in a hemoglobin based species.

Your people's hemoglobin was redesigned and your circulatory system responds to different partial pressures of oxygen and carbon dioxide.

Things like one liter of hemoglobin and three grams of assorted enzymes were offered for sale in terms of one slunk fifty and three slunks forty-five.