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gender dysphoria

n. A profound and persistent unhappiness related to one's physical sex.

Wikipedia
Gender dysphoria

Gender dysphoria or gender identity disorder (GID) is the dysphoria (distress) a person experiences as a result of the sex and gender they were assigned at birth. There is evidence suggesting that people who identify with a gender different from the one they were assigned at birth may do so not just due to psychological or behavioral causes, but also biological ones related to their genetics, the makeup of their brains, or exposure to hormones before birth.

Estimates of the prevalence of gender dysphoria or GID range from a lower bound of 1:2000 (or about 0.05%) in the Netherlands and Belgium to 0.5% of Massachusetts adults to 1.2% of New Zealand high-school students. These numbers are based on those who identify as transgender. It is estimated that about 0.005% to 0.014% of males and 0.002% to 0.003% of females would be diagnosed with gender dysphoria, based on current diagnostic criteria. Research indicates people who transition in adulthood are up to three times more likely to be male assigned at birth, but that among people transitioning in childhood the sex ratio is close to 1:1.

GID is classified as a disorder by the ICD-10 CM and DSM-5 (called gender dysphoria). Some transgender people and researchers support declassification of GID because they say the diagnosis pathologizes gender variance, reinforces the binary model of gender, and can result in stigmatization of transgender individuals. The official reclassification as gender dysphoria in the DSM-5 may help resolve some of these issues, because the term gender dysphoria applies only to the discontent experienced by some persons resulting from gender identity issues. The American Psychiatric Association, publisher of the DSM-5, states that "gender nonconformity is not in itself a mental disorder. The critical element of gender dysphoria is the presence of clinically significant distress associated with the condition."

The current main psychiatric approaches to treatment for persons diagnosed with GID are psychotherapy or to support the individual's preferred gender through hormone therapy, gender expression and role, or surgery.