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Fluorophosphates

Fluorophosphates (FPO), created when a fluoride ion reacts with phosphate molecules, inhibit enolase enzymes which can halt the process of glycolysis. FPO complexes with enolase and an Mg metal cofactor located in the active site to irreversibly deactivate the enzyme. In regards to bacterial microbes in a mouth, when exposed to fluoride their process of normal glucose metabolism is disrupted which in turn can decrease the amount of plaque build up and prevent the overpopulation of potentially antagonistic bacteria such as various species of Streptococcus.

Category:Fluorophosphates Category:Glucose Category:Dentistry Category:Biochemistry