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n. (context Hartlepool English) A snug woolly hat.


DUT is an acronym for

  • Da Nang University of Technology in Da Nang, Viet Nam
  • Dalian University of Technology in Dalian, China
  • Delft University of Technology in Delft, the Netherlands
  • Device under test, especially in semiconductor testing
  • DiplĂ´me universitaire de technologie, a French undergraduate university degree in technology
  • Durban University of Technology in Durban, South Africa
  • DUT (gene), which encodes DUTP pyrophosphatase
  • Drinking-up time, a former feature of United Kingdom alcohol licensing law
  • DUT1 or DUT, which describes the difference between coordinated universal time (UTC) and universal time (UT)
  • Unalaska Airport (IATA airport code "DUT"), an airport in Unalaska, Alaska, U.S.
DUT (gene)

DUTP pyrophosphatase, also known as DUT, is an enzyme which in humans is encoded by the DUT gene on chromosome 15.

This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotrimeric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.

Usage examples of "dut".

Dut his pride determined him, on his departure, to bury it while he fancied that he was unespied by all the world.

This hathel helde3 hym in and the halle entres, Driuande to the he3e dece, dut he no wothe, Haylsed he neuer one, bot he3e he ouer loked.

But-for dify ferent personal reasons-both were aware that instructor pilot dut was better for them than an assignment to a fighter squadron or to an attack torpedo squadron aboard a carrier or to observation plane S catapulted from a battleship would have been.