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'''Dhap ''' is a market center in Api Municipality in Darchula District in the Mahakali Zone of western Nepal. The formerly Village Development Committee was merged to form new municipality since 18 May 2014. At the time of the 1991 Nepal census it had a population of 4092 people living in 694 individual households. The major ethnic group living in Dhap are Brahmins and Chhetris with the majority of Bista(Brahmin), Joshi, Bhatta, Raikhola caste. Temple of God Malikarjun and Temple of God Latinath are two main religious sites. The main educational institute is Malikarjun Higher Secondary School and College, where one can study up to Undergraduate level from Elementary Level.

The settlement of village of Dhap can be compared to a small valley. It is situated on the bank of Mahakali River with high hills around it. Thaligad, One of the major stream in the district flows through the heart of Dhap. The staple food is Bhat(Steamed Rice) and Dal(Cereals and Pulses) or Palyau(Cereal Paste cooked with diluted yoghurt). One can also enjoy the fresh water fish found in the Mahakali River. The village of Dhap is independent in terms of agricultural production. Irrigation from Thaligad, local river helps peoples grow ample amount of crops for consumption.

DHAP (chemotherapy)

DHAP in context of chemotherapy is an acronym for chemotherapy regimen that is used for remission induction in cases of relapsed or refractory Non-Hodgkin lymphoma and Hodgkin disease. It is usually given for 2-3 courses, then followed by high-dose chemotherapy and autologous stem cell transplant. In combination with anti-CD20 monoclonal antibody Rituximab (Rituxan, Mabthera) it is called R-DHAP or DHAP-R.

[R]-DHAP regimen consists of:

  1. Rituximab, a monoclonal antibody, directed at B-cell surface antigen CD20
  2. (D)examethasone, a glucocorticoid hormone
  3. (H)igh-dose (A)ra-C - cytarabine, an antimetabolite;
  4. (P)latinol (cisplatin), a platinum-based antineoplastic agent with an alkylating mechanism;