changeofheart Second thoughts Attitude reversal Reversal in attitude Profound shift in outlook Decision alteration 2008 Jodi Picoult novel ... or a hint to the puzzle theme EARTH Decision reversal ... or, literally, what can be found inside 17-, 22-, 49- and 58-Across Cardiologist's drastic remedy? Conversion Chief exec has to swing wavering father in rethink Shift in compassion causing second thoughts