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Answer for the clue "Founded a line of kings who reigned in Asia Minor until 65 BC (358-281 BC) ", 8 letters:
seleucus

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Seleucus was a wealthy Christian Roman Senator of Greek descent who lived in the second half of the 4th century and first half of the 5th century. One of the parents of Seleucus, was the sibling to the great Christian Saint Olympias . Seleucus had one sibling, ...