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Answer for the clue "Macedonian general who accompanied Alexander the Great into Asia ", 8 letters:
seleucus

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Seleucus ( Seleukos ) was in 30 BC a commandant of the eastern Egyptian border-fortress Pelusium . In the final stage of the decisive war between Mark Antony and Octavian for the sole rule of the Roman Empire Antony and his lover, the Egyptian queen Cleopatra ...