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Answer for the clue "An abnormally large amount of this fetoprotein in the fetus can signal an abnormality of the neural tube (as spina bifida or anencephaly) ", 3 letters:
afp

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Wikipedia Word definitions in Wikipedia
AFP is an Australian factual television show that looks at the everyday workings of the Australian Federal Police . It follows AFP investigations and operations in people smuggling, counter terrorism, bomb disposal, international drug syndicates, child ...

Wiktionary Word definitions in Wiktionary
init. 1 (context in Australia English) (initialism of Australian federal Federal police Police English) (Established 1979) 2 (context journalism in France English) (initialism of agence Agence France France-presse Presse English) 3 (context in US English) ...