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Answer for the clue "Biblical patriarch whose name means "he will laugh" ", 4 letters:
isac

Word definitions for isac in dictionaries

Wikipedia Word definitions in Wikipedia
ISAC may refer to: internet Speech Audio Codec (as "iSAC"), a wideband speech codec, developed by Global IP Solutions (GIPS) Institute for the Study of American Cultures , a defunct organization devoted to the study of pre-Columbian contact between the ...