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Xyleborini are a tribe of ambrosia beetles (alternatively called subtribe Xyleborina of tribe Scolytini), highly specialized weevils of the subfamily Scolytinae. Much of the ambrosia beetle fauna in Eurasia and the Americas consists of Xyleborini species. Some Xyleborini are notorious invasive species.

Most genera are small or even monotypic, and contain 1-8 dozen species. The type genus Xyleborus contains over 500 species, but it is an unnatural grouping of unrelated species. Key for the world genera of Xyleborini available through a North Carolina State University website.