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WSEN may refer to:

  • WSEN (AM), a radio station (1050 kHz) licensed to Baldwinsville, New York, United States
  • WSEN-FM, a radio station (103.9 MHz) licensed to Mexico, New York, United States
  • WOLF-FM, a radio station (92.1 MHz) licensed to Baldwinsville, which used the call sign WSEN-FM from 1967 to 2016

WSEN (AM 1050) is a radio station serving Baldwinsville in the Syracuse, New York metropolitan area. The station airs an oldies format stretching from the 1950s through the 1960s and a very few early 1970s. WSEN is owned by Leatherstocking Media Group.