Wikipedia
Winkte (also spelled wíŋtke) is the contraction of an old Lakota word, Winyanktehca, meaning "wants to be like a woman." Winkte are a social category in Lakota culture, of male assigned at birth people who adopt the clothing, work, and mannerisms that Lakota culture usually consider feminine. Usually winkte are homosexual, though they may or may not consider themselves part of the more mainstream gay or transgender communities. Many modern winkte participate in the pan-Indian Two-Spirit community.
While historical accounts of their status vary, most accounts see the winkte as regular members of the community, and not in any way marginalized for their status. Other accounts hold the winkte as sacred, occupying a liminal, third gender role in the culture and born to fulfill ceremonial roles that can not be filled by either men or women. In contemporary Lakota communities, attitudes towards the winkte vary.