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Saridon

Saridon is an analgesic combination indicated for the management of headache. The currently global base formulation contains 135 mg of propyphenazone, 260 mg of paracetamol and 55 mg of caffeine. The combination is designed and said to produce effective analgesia with fast onset of action in 15 minutes, as compared to paracetamol, ibuprofen, or aspirin alone.

It was first launched by Roche in 1933, containing initially pyrithyldione and phenacetin, widely used remedies for fever and pain. It often took on the form “A.P.C” (aspirin-phenacetin-caffeine) but Saridon was reformulated in 1981; replacing the original ingredient phenacetin with paracetamol before the US FDA recall in 1983. It is available in more than 80 countries across Europe, Latin America, Asia and Africa.