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Ruberlysin

Ruberlysin (, Crotalus ruber metalloendopeptidase II, hemorrhagic toxin II) is an enzyme. This enzyme catalyses the following chemical reaction

Cleavage of His-Leu, Ala-Leu, Tyr-Leu and Gly-Phe bonds in the B chain of insulin; His-Pro, Pro-Phe, and Trp-Ser of angiotensin I; and Gly-Phe of Met enkephalin

This endopeptidase is present in the venom of the red rattlesnake ( Crotalus ruber ruber).