Wiktionary
n. (context physics English) A hypothetical point-like particle, supposed to be a subcomponent of quarks and leptons.
Wikipedia
In particle physics, preons are "point-like" particles, conceived to be subcomponents of quarks and leptons. The word was coined by Jogesh Pati and Abdus Salam in 1974. Interest in preon models peaked in the 1980s but has slowed as the Standard Model of particle physics continues to describe the physics mostly successfully, and no direct experimental evidence for lepton and quark compositeness has been found.
Note that in the hadronic sector there are some intriguing open questions and some effects considered anomalies within the Standard Model. For example, four very important open questions are the proton spin puzzle, the EMC effect, the distributions of electric charges inside the nucleons as found by Hofstadter in 1956, and the ad hoc CKM matrix elements.