Wiktionary
n. 1 (context chiefly Mahayana Buddhism English) The principle that everything is (l en interdependent), that all things arise in dependence upon multiple causes and conditions. 2 (context chiefly Theravada Buddhism English) The (w: Twelve Nidānas).
Wikipedia
Pratītyasamutpāda (; paṭiccasamuppāda), commonly translated as dependent origination, or dependent arising, states that all dharmas ("things") arise in dependence upon other dharmas: "if this exists, that exists; if this ceases to exist, that also ceases to exist." It is a pragmatic teaching, which is applied to dukkha (suffering) and the cessation of dukkha.
The principle is applied in the twelve links of dependent origination doctrine in Buddhism, which describes the chain of causes which result in rebirth and dukkha. By breaking the chain, liberation from this endless cycles of rebirth and dukkha can be attained. Everything except nirvana (nibbana) are the consequence of Pratītyasamutpāda, asserts Buddhism. This principle complements its teachings of anicca and anatta.