What is "oxaflozane"

n. An antidepressant and anxiolytic drug.

Oxaflozane ( INN) (brand name Conflictan) is an antidepressant and anxiolytic drug that was introduced by Solvay in France in 1982 for the treatment of depression but has since been discontinued. It is a prodrug of flumexadol (N-dealkyloxaflozane; 2-(3-trifluoromethylphenyl)morpholine; CERM-1841 or 1841-CERM), which is reported to act as an agonist of the serotonin 5-HT (pK = 7.1) and 5-HT (pK = 7.5) receptors and, to a much lesser extent, of the 5-HT (pK = 6.0) receptor. In addition to its serotonergic properties, oxaflozane may also produce anticholinergic side effects at high doses, namely in overdose.