What is "ocrl"

Inositol polyphosphate 5-phosphatase OCRL-1 (INPP5F), also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans.

This gene encodes a phosphatase enzyme involved in actin polymerization, and is found in the trans- Golgi network.

Mutation in this gene are associated with oculocerebrorenal syndrome and also with Dent's disease.