What is "obscurin"

n. (context biochemistry English) A protein in humans, related to titin and nebulin.

Obscurin is a protein that in humans is encoded by the OBSCN gene. Obscurin belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin. Obscurin is expressed in cardiac and skeletal muscle, and plays a role in the organization of myofibrils during sarcomere assembly. A mutation in the OBSCN gene has been associated with hypertrophic cardiomyopathy and altered obscurin protein properties have been associated with other muscle diseases.