What is "nucleoside-triphosphatase"

In enzymology, a nucleoside-triphosphatase is an enzyme that catalyzes the chemical reaction

NTP + HO $\rightleftharpoons$ NDP + phosphate

Thus, the two substrates of this enzyme are NTP and HO, whereas its two products are NDP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is unspecific diphosphate phosphohydrolase. Other names in common use include nucleoside triphosphate phosphohydrolase, nucleoside-5-triphosphate phosphohydrolase, and nucleoside 5-triphosphatase. This enzyme participates in purine metabolism and thiamine metabolism.