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The Collaborative International Dictionary
nicotinamide

niacinamide \niacinamide\ n. The amide of niacin (nicotinic acid), called also nicotinamide. It was at one time called vitamin B3, and can function to relieve nicotinic acid deficiency. Chemical formula C6H6N2O, chemically it is 3-pyridinecarboxamide.

Syn: nicotinic acid amide, nicotinamide.

Wiktionary
nicotinamide

n. (context vitamin biochemistry organic compound English) The amide of nicotinic acid (or niacin).

WordNet
Wikipedia
Nicotinamide

Nicotinamide, also known as niacinamide, NAA, and nicotinic amide, is the amide of nicotinic acid (vitamin B / niacin). Nicotinamide is a water-soluble vitamin and is part of the vitamin B group. Nicotinic acid, also known as niacin, is converted to nicotinamide in vivo, and, though the two are identical in their vitamin functions, nicotinamide does not have the same pharmacological and toxic effects of niacin, which occur incidental to niacin's conversion. Thus nicotinamide does not reduce cholesterol or cause flushing, although nicotinamide may be toxic to the liver at doses exceeding 3 g/day for adults. In cells, niacin is incorporated into nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), although the pathways for nicotinic acid amide and nicotinic acid are very similar. NAD+ and NADP+ are coenzymes in a wide variety of enzymatic oxidation-reduction reactions. Commercial production of niacin and niacinamide (several thousand tons annually) is by hydrolysis or aminolysis of 3-cyanopyridine (nicotinonitrile).

Small intestinal bacterial overgrowth is one known cause of nicotinamide deficiency.

Usage examples of "nicotinamide".

It was only the light—violet-blue and orange-red—that mattered, the incredible shower of photons that excited her chlorophyll, passing electrons down carrier molecules to form adenosine diphosphate and nicotinamide adenine dinucleo .