What is "nicotinamidase"

n. (context enzyme English) A hydrolase enzyme that catalyzes the chemical reaction ''nicotinamide + H₂O $rightleftharpoons$ nicotinate + NH₃''.

In enzymology, a nicotinamidase is an enzyme that catalyzes the chemical reaction

nicotinamide + HO $\rightleftharpoons$ nicotinate + NH

Thus, the two substrates of this enzyme are nicotinamide and HO, whereas its two products are nicotinate and NH.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is nicotinamide amidohydrolase. Other names in common use include nicotinamide deaminase, nicotinamide amidase, and YNDase. This enzyme participates in nicotinate and nicotinamide metabolism.