What is "neopterin"

n. (context biochemistry English) A pteridine, ''2-amino-6-(1,2,3-trihydroxypropyl)-1H-pteridin-4-one'', that is a catabolic product of guanosine triphosphate

Neopterin is a catabolic product of guanosine triphosphate (GTP), a purine nucleotide.

Neopterin belongs to the chemical group known as pteridines. It is synthesised by human macrophages upon stimulation with the cytokine interferon-gamma and is indicative of a pro-inflammatory immune status. Neopterin serves as a marker of cellular immune system activation.