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naringin

n. The major flavonoid glycoside in grapefruit, giving the fruit its bitter taste, which is metabolized to the flavanone naringenin in humans.

Wikipedia
Naringin

Naringin is a flavanone-7-O- glycoside between the flavanone Naringenin and the disaccharide neohesperidose. The flavonoids naringenin and hesperetin, which form the aglycones of naringin and hesperidin, occur naturally in citrus fruits, especially in grapefruit, where naringin is responsible for the fruit's bitter taste. In commercial grapefruit juice production, the enzyme naringinase can be used to remove the bitterness created by naringin. In humans the naringin is metabolized to the flavanone naringenin.