Find the word definition

Crossword clues for myxedema

The Collaborative International Dictionary
myxedema

myxedema \myxedema\ n. (Med.) A pathological condition due to severe hyperthyroidism, marked by dry skin and swellings around lips and nose as well as mental and physical deterioration. [Also spelled myx[oe]dema.]

myxedema

Myxoedema \Myx`[oe]*de"ma\, n. [NL. fr. Gr. ? mucus + [oe]dema.] (Med.) A disease producing a peculiar cretinoid appearance of the face, slow speech, and dullness of intellect, and due to failure of the functions of the thyroid gland. [Also spelled myxedema.]-- Myx`[oe]*dem"a*tous, a., Myx`[oe]*dem"ic, a.

Wiktionary
myxedema

n. (context pathology English) A form of cutaneous and dermal edema that is secondary to increased deposition of connective tissue components in subcutaneous tissue.

WordNet
myxedema

n. hypothyroidism marked by dry skin and swellings around lips and nose as well as mental deterioration [syn: myxoedema]

Wikipedia
Myxedema

Myxedema or myxoedema is a term used synonymously with severe hypothyroidism. It is also used to describe a dermatological change that can occur in hypothyroidism, and some forms of hyperthyroidism. Also called as Gull's disease is the main symptom of underactive thyroid gland(e.g.: hashimoto's thyroiditis).This article discusses the dermatological changes.

In this context, myxedema refers to deposition of mucopolysaccharides in the dermis, which results in swelling of the affected area. One manifestation of myxedema occurring in the lower limb is pretibial myxedema, a hallmark of Graves disease, an autoimmune form of hyperthyroidism. Myxedema can also occur in Hashimoto's thyroiditis and other long-standing forms of hypothyroidism.

The word myxedema originates from , taken from ancient Greek to convey 'mucus' or 'slimy substance', and for "swelling". It can also be thought as nonpitting edema, in contrast to pitting edema.

Usage examples of "myxedema".

Recently, Leichtenstein, observing in a case of myxedema treated with the thyroid gland that the subcutaneous fat disappeared with the continuance of the treatment, was led to adopt this treatment for obesity itself and reports striking results.

The removal of the thyroid might result in severe myxedema, but the patient at least remains alive.

He holds that the observations in myxedema, in obesity, and psoriasis warrant the belief that the thyroid gland eliminates a material having a regulating influence upon the constitution of the panniculus adiposus and upon the nutrition of the skin in general.

The disease is not myxedema because there is no peculiar physiognomy, no spade-like hands nor infiltrated skin, no alteration of the speech, etc.

Marie regards the disease as a systemic dystrophy analogous to myxedema, due to a morbid condition of the pituitary body, just as myxedema is due to disease of the thyroid.

A condition akin to myxedema occurs after operative removal of the thyroid gland.

Brissaud shows the intimate relation between myxedema, endemic cretinism, sporadic cretinism, or myxedematous idiocy, and infantilism.

Figure 285 shows a case of myxedema, one of myxedema in a case of arrested development--a transition case between myxedema of the adult and sporadic cretinism--and a typical case of sporadic cretinism.