Crossword clues for morphine
Longman Dictionary of Contemporary English
The Collaborative International Dictionary
Douglas Harper's Etymology Dictionary
chief alkaloid of opium, 1828, from French morphine or German Morphin (1816), name coined by German apothecary Friedrich Sertürner (1783-1840) in reference to Latin Morpheus, Ovid's name for the god of dreams, from Greek morphe "form, shape, beauty, outward appearance," perhaps from PIE *merph-, a possible Greek root meaning "form," of unknown origin. So called because of the drug's sleep-inducing properties.
n. A crystalline alkaloid (7,8-didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol), extracted from opium, the salts of which are soluble in water and are used as analgesics, anaesthetics and sedatives; it is one of a group of morphine alkaloids.
n. an alkaloid narcotic drug extracted from opium; a powerful, habit-forming narcotic used to relieve pain [syn: morphia]
Morphine, sold under many trade names, is a pain medication of the opiate type. It acts directly on the central nervous system (CNS) to decrease the feeling of pain. It can be used for both acute pain and chronic pain. Morphine is also frequently used for pain from myocardial infarction and during labour. It can be given by mouth, by injection into a muscle, by injecting under the skin, intravenously, into the space around the spinal cord, or rectally. Maximum effect is around 20 min when given intravenously and 60 min when given by mouth while duration of effect is between three and seven hours. Long-acting formulations also exist.
Potentially serious side effects include a decreased respiratory effort and low blood pressure. Morphine has a high potential for addiction and abuse. If the dose is reduced after long-term use, withdrawal may occur. Common side effects include drowsiness, vomiting, and constipation. Caution is advised when used during pregnancy or breast feeding, as morphine will affect the infant.
Morphine was first isolated between 1803 and 1805 by Friedrich Sertürner. This is generally believed to be the first isolation of an active ingredient from a plant. Merck began marketing it commercially in 1827. Morphine was more widely used after the invention of the hypodermic syringe in 1853–1855. Sertürner originally named the substance morphium after the Greek god of dreams, Morpheus, for its tendency to cause sleep.
The primary source of morphine is isolation from poppy straw of the opium poppy. In 2013, an estimated 523,000 kilograms of morphine were produced. About 45,000 kilograms were used directly for pain, an increase over the last twenty years of four times. Most use for this purpose was in the developed world. About 70% of morphine is used to make other opioids such as hydromorphone, oxycodone and heroin. It is a Schedule II drug in the United States, Class A in the United Kingdom, and Schedule I in Canada. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.
Morphine is a potent opiate analgesic drug.
Morphine may also refer to:
- Morphine (band), an American alternative rock group
- Morphine (film), a 2008 Russian film by Aleksei Balabanov
- "Morphine", a song by Michael Jackson from Blood on the Dance Floor: HIStory in the Mix
Morphine is a 2008 Russian film by Aleksei Balabanov.
The film is based on semi-autobiographical short stories by Mikhail Bulgakov.
Morphine was an American alternative rock group formed by Mark Sandman, Dana Colley, and Jerome Deupree in Cambridge, Massachusetts in 1989. After five successful albums and extensive touring, they disbanded in 1999 after frontman Sandman died of a heart attack.
Morphine combined blues and jazz elements with more traditional rock arrangements, giving the band an unusual sound. Sandman sang distinctively in a "deep, laid-back croon", and his songwriting featured a prominent beat influence. The band themselves coined the label "low rock" to describe their music, which involved "a minimalist, low-end sound that could have easily become a gimmick: a " power trio" not built around the sound of an electric guitar. Instead, with sly intelligence, Morphine expanded its offbeat vocabulary on each album."
The band enjoyed positive critical appraisal, but met with mixed results commercially. In the United States the band was embraced and promoted by the indie rock community, including public and college radio stations and MTV's 120 Minutes, which the band once guest-hosted, but received little support from commercial rock radio and other music television programs. This limited their mainstream exposure and support in their home country, while internationally they enjoyed high-profile success, especially in Belgium, Portugal, France and Australia.
Usage examples of "morphine".
Thus, in experimental animals the phenolic hydroxyl group of morphine has been shown to be susceptible to methylation both in vivo and in vitro, with the resultant formation of codeine.
These are N-demethylation to form norcodeine, 0-demethylation to morphine, and glucuronide formation.
O-demethylated metabolite morphine and the glucuronidated morhpine metabolite M6G.
Our boy Graham cold-cocked him from behind with the whiskey bottle, gave him a veinful of morphine, cleaned out the safe, and tiptoed home through the tulips.
Dr Strout, are you saying that twelve milligrams of morphine injected directly into the vein is sufficient to cause death?
Mr Russo did fall unconscious from the combined effect of alcohol and morphine, it is true, is it not, that this scenario is not consistent with Sal Russo having administered the morphine himself?
On the morphine, for example, Sal asked if twelve milligrams could be a lethal dose.
I brought this gun with me, just in case, but then there was the morphine out on the table.
He had hated being a morphine junkie, but he had liked how it made him feel.
Reaching down, he gripped his leg, splaying his fingers across the fabric of his pants and listened as the little vials of morphine clicked together quietly in his pocket.
The junkie remembered how to poke the needle through the foil cap on the morphine just so, then to invert the vial and pull back the stopper on the syringe.
Dylan or because of his indiscretions with morphine seemed to dissolve immediately, and from that moment on Kat and Eric were friends, bound by that hot, humid August afternoon when they had each shared a dark and brooding secret.
Eric shook his head, feeling the morphine sweep over him in a heavy, soothing cloak.
He had pumped the morphine into one of the many IV tubes sticking out of Eric.
And why would he be up on Palliative Care giving out morphine in the first place?