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Mewtwo

is a fictional creature from Nintendo and Game Freak's Pokémon media franchise. Created by Ken Sugimori, it first appeared in the video games Pokémon Red and Blue and their sequels, and later appeared in various merchandise, spinoff titles, as well as animation adaptations of the franchise. Masachika Ichimura voiced the franchise's original Mewtwo character in Japanese, and the creature's younger self is voiced by Fujiko Takimoto in the Sound Picture Box: Mewtwo's Origin CD drama and Showtaro Morikubo in the anime adaptation. In English, Jay Goede voiced Mewtwo in Mewtwo Strikes Back and the Pokémon Live! musical. For the former production, he was credited under the pseudonym "Philip Bartlett". Dan Green provided the voice in Mewtwo Returns. Actress Reiko Takashima voices a separate Mewtwo character in the prequel special Mewtwo: Prologue to Awakening and the film ExtremeSpeed Genesect: Mewtwo Awakens; this second Mewtwo is voiced by actress Miriam Pultro in the English dub.

In the video games, the player can fight and capture Mewtwo to pit it against other Pokémon. The player first learns of Mewtwo late in Pokémon Red and Blue by reading research documents left in a ruined laboratory on Cinnabar Island. The documents reveal that a solitary scientist spent years genetically engineering a descendant of the Pokémon Mew. Mewtwo eventually escaped after proving too strong to contain.

Regarded as one of the series' strongest Pokémon, it changed the way players approached the games by forcing them to find ways to counteract those using Mewtwo. Studies found the character popular with older male children, which contrasted with its counterpart Mew. Reactions to the creature's first anime portrayal have been divided, as reviewers such as Daily Record cited it as a cliché villain, while others such as Animerica and Sight & Sound praised the character's depth.