n. (context physiology English) A series of chemical reactions occurring within a cell.
In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites, which are modified by a sequence of chemical reactions catalyzed by enzymes. In a metabolic pathway, the product of one enzyme acts as the substrate for the next. These enzymes often require dietary minerals, vitamins, and other cofactors to function.
Different metabolic pathways function based on the position within a eukaryotic cell and the significance of the pathway in the given compartment of the cell. For instance, the citric acid cycle, electron transport chain, and oxidative phosphorylation all take place in the mitochondrial membrane. In contrast, glycolysis, pentose phosphate pathway, and fatty acid biosynthesis all occur in the cytosol of a cell.
There are two types of metabolic pathways that are characterized by their ability to either synthesize molecules with the utilization of energy ( anabolic pathway) or break down of complex molecules by releasing energy in the process ( catabolic pathway). The two pathways compliment each other in that the energy released from one is used up by the other. The degradative process of a catabolic pathway provides the energy required to conduct a biosynthesis of an anabolic pathway. In addition to the two distinct metabolic pathways is the amphibolic pathway, which can be either catabolic or anabolic based on the need for or the availability of energy.
Pathways are required for the maintenance of homeostasis within an organism and the flux of metabolites through a pathway is regulated depending on the needs of the cell and the availability of the substrate. The end product of a pathway may be used immediately, initiate another metabolic pathway or be stored for later use. The metabolism of a cell consists of an elaborate network of interconnected pathways that enable the synthesis and breakdown of molecules ( anabolism and catabolism)
Usage examples of "metabolic pathway".
And a group of militant anti-GM campaigners are being pursued by Interpol, after their announcement that they have spliced a metabolic pathway for cyanogenic glycosides into maize seed corn destined for human-edible crops.
One by one, a fraction of the tags changed from green to red, marking passage through the first stage of the metabolic pathway: the attachment of an energy-rich cluster of atoms-more or less the Autoverse equivalent of a phosphate group.
One by one, a fraction of the tags changed from green to red, marking passage through the first stage of the metabolic pathway: the attachment of an energy-rich cluster of atoms.
One by one, a fraction of the tags changed from green to red, marking passage through the first stage of the metabolic pathway: the attachment of an energy-rich cluster of atomsmore or less the Autoverse equivalent of a phosphate group.
In a male pseudoher-maphrodite with an enzyme defect, there is normal development of the male structures dependent on enzymes that act at the steps of the metabolic pathway before the defective enzyme.
His article attacks Tanida's theory of enzyme fusionthe concept of changing the chemical structure of the enzyme blocking the step in the metabolic pathway.
It sometimes happened that if the mechanism to digest the primary food was disabled, mutations were possible that could create an alternative metabolic pathway to exploit a different food instead.