What is "mafosfamide"

n. A particular drug used in the treatment of cancer.

Mafosfamide ( INN) is an oxazaphosphorine ( cyclophosphamide-like) alkylating agent under investigation as a chemotherapeutic. It is metabolized by cytochrome P450 into 4-Hydroxycyclophosphamide, which is then converted into aldophosphamide, which, in turn yields the cytotoxic metabolites phosphoramide mustard and acrolein.

Several Phase I trials have been completed.