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The Collaborative International Dictionary
Metabolite

Metabolite \Me*tab"o*lite\, n. (Physiol Chem.) A product of metabolism; a substance produced by metabolic action, as urea.

Wiktionary
metabolite

n. Any substance produced by, or taking part in, a metabolic reaction.

WordNet
metabolite

n. any substance involved in metabolism (either as a product of metabolism or as necessary for metabolism)

Wikipedia
Metabolite

Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan. Some sugars that are metabolites; example: fructose or glucose in the metabolic pathways.

Examples of primary metabolites produced by industrial microbiology:

Class

Example

Alcohol

Ethanol

Amino acids

Glutamic acid, aspartic acid

Nucleotides

5' guanylic acid

Antioxidants

Isoascorbic acid

Organic acids

Acetic acid, lactic acid

Polyols

Glycerol

Vitamins

B

The metabolome forms a large network of metabolic reactions, where outputs from one enzymatic chemical reaction are inputs to other chemical reactions.

Metabolites from chemical compounds, whether inherent or pharmaceutical, are formed as part of the natural biochemical process of degrading and eliminating the compounds. The rate of degradation of a compound is an important determinant of the duration and intensity of its action. Profiling metabolites of pharmaceutical compounds, drug metabolism, is an important part of drug discovery, leading to an understanding of any undesirable side effects.

Usage examples of "metabolite".

Sugars, acetone bodies, creatine, nitrogenous compounds, haemoglobin, myoglobin, amino acids and metabolites, uric acid, urea, urobilinogen and coproporphyrins, bile pigments, minerals, fats, and of course a great variety of psychotropic drugs: certainly all of the ones proscribed by the US Federal Bureau of Narcotics.

Ordinarily, monoamine oxidase brings about the oxidation of serotonin into a normal metabolite, one in which the nitrogen atoms have been removed.

Supreme Court should rule against Metabolite, and the Patent Office should begin to reverse its strategy of patenting strategies.

The Supreme Court should rule against Metabolite, and the Patent Office should begin to reverse its strategy of patenting strategies.

Although Metabolite does not have a monopoly on test methodsother companies make homocysteine tests, toothey assert licensing rights on the correlation of elevated homocysteine with vitamin deficiency.

O-demethylated metabolite morphine and the glucuronidated morhpine metabolite M6G.

This is an abnormal metabolite, since it does not seem that adrenalin in the body normally passes through the adrenochrome stage.

However, since 1954, when this suggestion was first made, all attempts to locate adrenochrome or other abnormal metabolites of adrenalin in mental patients have failed.

Morphine is also a metabolite of codeine, and when codeine is metabolized in the blood we get very low levels of morphine.

One abnormal metabolite looming as a possibility is bufotenin, a "toad poison" — that is, one of a group of toxic substances found in the parotid glands of toads.

If a man was a heroin and cocaine addict, his dead body displays the needle tracks, and the metabolites morphine and benzoylecgonine show up in urine, the vit­.

If a man was a heroin and cocaine addict, his dead body displays the needle tracks, and the metabolites morphine and benzoylecgonine show up in urine, the vitreous fluid of the eye, and the blood.

Gabriel Nahas' 1970s studies, tried to somehow connect the THC metabolites routinely found in the fatty tissue of human brains, reproductive organs, and other fatty areas of the body to the dead brain cells in the suffocated monkeys.

The leftover THC metabolites then attach themselves, in a very normal way, to fatty deposits, for the body to dispose of later, which is a safe and perfectly natural process.

Most are not dangerous and THC metabolites show less toxic* potential than virtually any known metabolic leftovers in your body!