Wikipedia
Lysidine is a derivative of 2-imidazoline derivative. It is a colorless solid with basic properties and soluble in organic solvents. It is used as a precursor to other compounds of pharmaceutical interest.
Lysidine is an uncommon nucleoside, rarely seen outside of tRNA. It is a derivative of cytidine in which the carbonyl is replaced by the amino acid lysine. The third position in the anti-codon of the Isoleucine-specific tRNA, is typically changed from a cytidine which would pair with guanosine to a lysidine which will base pair with adenosine. Uridine could not be used at this position even though it is a conventional partner for adenosine since it will also " wobble base pair" with guanosine. So lysidine allows better translation fidelity.
Lysidine may refer to either of two unrelated chemical compounds:
- Lysidine (nucleoside) (CHNO), a nucleoside
- Lysidine (chemical) (CHN), an imidazoline