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The Collaborative International Dictionary

Lymphoma \Lym*pho"ma\, n. [NL. See Lymph, and -oma.] (Med.) A tumor having a structure resembling that of a lymphatic gland; -- called also lymphadenoma.

Malignant lymphoma, a fatal disease characterized by the formation in various parts of the body of new growths resembling lymphatic glands in structure.

Douglas Harper's Etymology Dictionary

plural lymphomata, 1867, from lymph + -oma.


n. (context oncology pathology English) a malignant tumor that arises in the lymph nodes or in other lymphoid tissue

  1. n. a neoplasm of lymph tissue that is usually malignant; one of the four major types of cancer

  2. [also: lymphomata (pl)]


Lymphoma is a group of blood cell tumors that develop from lymphatic cells. The name often refers to just the cancerous ones rather than all such tumors. Signs and symptoms may include enlarged lymph nodes, fever, drenching sweats, unintended weight loss, itching, and feeling tired. The enlarged lymph nodes are usually painless. The sweats are most common at night.

There are dozens of subtypes of lymphomas. The two main categories of lymphomas are Hodgkin lymphomas (HL) and the non-Hodgkin lymphomas (NHL). The World Health Organization (WHO) includes two other categories as types of lymphoma: multiple myeloma and immunoproliferative diseases. About 90% of lymphomas are non-Hodgkin lymphomas. Lymphomas and leukemias are a part of the broader group of tumors of the hematopoietic and lymphoid tissues.

Risk factors for Hodgkin lymphoma include infection with Epstein–Barr virus and a history of the disease in the family. Risk factors for common types of non-Hodgkin lymphomas include autoimmune diseases, HIV/AIDS, infection with human T-lymphotropic virus, immunosuppressant medications, and some pesticides. Eating large amounts of red meat may also increase the risk. Diagnosis, if enlarged lymph nodes are present, is usually by lymph node biopsy. Blood, urine, and bone marrow testing may also be useful in the diagnosis. Medical imaging may then be done to determine if and where the cancer has spread. Lymphoma most often spreads to the lungs, liver, and/or brain.

Treatment may involve one or more of the following: chemotherapy, radiation therapy, targeted therapy, and surgery. In some non-Hodgkin lymphomas, an increased amount of protein produced by the lymphoma cells causes the blood to become so thick that plasmapheresis is performed to remove the protein. Watchful waiting may be appropriate for certain types. The outcome depends on the subtype with some being curable and treatment prolonging survival in most. The five-year survival rate in the United States for all Hodgkin lymphoma subtypes is 85%, while that for non-Hodgkin lymphomas is 69%. Worldwide, lymphomas developed in 566,000 people in 2012 and caused 305,000 deaths. They make up 3–4% of all cancers, making them as a group the seventh-most common form. In children, they are the third-most common cancer. They occur more often in the developed world than the developing world.

Usage examples of "lymphoma".

In January 2003, a woman named Sarah Pettit, the senior editor for the Newsweek Arts and Entertainment section, died of non-Hodgkin s lymphoma at the tragically young age of thirty- six.

Doc says it could be scar tissue, it could be the remains of a dying tumor, or it might be our old friend lymphoma cropping up again.

One afternoon I agreed to play a little golf with Bill Stapleton and another friend of ours named Dru Dunworth, who was a lymphoma survivor, at a club called Onion Creek.

Dana, only forty-four, had been diagnosed with non-Hodgkins lymphoma, but she appeared to be in remission.

For large-cell lymphoma, the cure rate today is around seventy percent.

I suffered from lymphoma some years back, and I was cured by a drug tailored to attack the cancerous cells.

It was lymphoma in both lungs and it had metastasized, meaning she had cancer all through her system, and they did not expect her to last more than a few days.

They were the House of God disasters, mostly young men and women with horrible diseases just past cure and just our side of death, diseases with rotting names like leukemia, melanoma, hepatoma, lymphoma, carcinoma, and all the other horrendomas for which there was no cure in this world or in any other.

This is especially true for cervical and liver cancers, as well as some lymphomas.

Growth-promoting effect of oestriol in a lymphoma lacking estrogen receptors.