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The Collaborative International Dictionary
Ligation

Ligation \Li*ga"tion\ (l[-i]*g[=a]"sh[u^]n), n. [L. ligatio, fr. ligare to bind. Cf. Liaison.]

  1. The act of binding, or the state of being bound.

  2. That which binds; bond; connection.

    Tied with tape, and sealed at each fold and ligation.
    --Sir W. Scott.

Douglas Harper's Etymology Dictionary
ligation

1590s, from Middle French ligation, from Late Latin ligationem (nominative ligatio), noun of action from past participle stem of ligare "to bind" (see ligament).

Wiktionary
ligation

n. 1 Something that ties, a ligature. 2 The act of tying, of applying a ligature. 3 The state of having a ligature, of being tied. 4 (context medicine English) The act of tying off or sealing a blood vessel or fallopian tube during surgery. 5 (context chemistry English) The formation of a complex by reaction with a ligand

WordNet
ligation

n. (surgery) tying a duct or blood vessel with a ligature (as to prevent bleeding during surgery)

Wikipedia
Ligation

Ligation may refer to:

  • Ligation (molecular biology), the covalent linking of two ends of DNA or RNA molecules, most commonly done using DNA ligase, RNA ligase (ATP) or other enzymes.
  • In medicine, the making of a ligature (tie)
  • Chemical ligation, the production of peptides from amino acids
  • Tubal ligation, a method of female sterilization
  • Rubber band ligation, a treatment for hemorrhoids
  • In Coordination chemistry, making a bond between a ligand and a Lewis acid
Ligation (molecular biology)

In molecular biology, ligation is the joining of two nucleic acid fragments through the action of an enzyme. It is an essential laboratory procedure in the molecular cloning of DNA whereby DNA fragments are joined together to create recombinant DNA molecules, such as when a foreign DNA fragment is inserted into a plasmid. The ends of DNA fragments are joined together by the formation of phosphodiester bonds between the 3'-hydroxyl of one DNA terminus with the 5'-phosphoryl of another. RNA may also be ligated similarly. A co-factor is generally involved in the reaction, and this is usually ATP or NAD.

Ligation in the laboratory is normally performed using T4 DNA ligase, however, procedures for ligation without the use of standard DNA ligase are also popular.

Usage examples of "ligation".

A small nick in the axillary vessel, a quick ligation of the ductus itself with a number-8 silk ligature.

Ehrlich, Ficker, Klein, Rodforffer, and the Ephemerides, all record instances in which a large tongue was removed either by ligation or amputation.

Veda: among them his divine birth is that which is distinguished by the ligation of the zone and sacrificial cord, and in that birth the Gayatri is his mother, and the Acharya his father.

This the obscure artist calls conjunction, sublimation, assation, extraction, putrefaction, ligation, desponsation, subtilization, generation, etc.

Flickman now was advocating mandatory tubal ligations for all single mothers applying for food stamps.

I tried to concentrate on what Blanche was saying, but all I could think about was that even at my age, a tubal ligation probably wasn't out of the question.