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Wiktionary
lidocaine

n. (context medicine English) A local anesthetic that is also used as a antiarrhythmic drug.

WordNet
lidocaine

n. a local anesthetic (trade names Lidocaine and Xylocaine) used topically on the skin and mucous membranes [syn: Xylocaine]

Wikipedia
Lidocaine

Lidocaine, also known as xylocaine and lignocaine, is a medication used to numb tissue in a specific area and to treat ventricular tachycardia. It can also be used for nerve blocks. Lidocaine mixed with a small amount of epinephrine is available to allow larger doses to be used as numbing and to make it last longer. When used as an injectable it typically begins working within four minutes and lasts for half an hour to three hours. Lidocaine may also be applied directly to the skin for numbing.

Common side effects with intravenous use include sleepiness, muscle twitching, confusion, changes in vision, numbness, tingling, and vomiting. It can cause low blood pressure and an irregular heart rate. There are concerns that injecting it into a joint can cause problems with the cartilage. It appears to be generally safe for use in pregnancy. A lower dose may be required in those with liver problems. It is generally safe to use in those allergic to tetracaine or benzocaine. Lidocaine is an antiarrhythmic medication of the class Ib type. Lidocaine works by blocking sodium channels and thus decreasing the rate of contractions of the heart. When used locally as a numbing agent, local neurons cannot signal the brain.

Lidocaine was discovered in 1946 and went on sale in 1948. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic healthcare system. It is available as a generic medication and is not very expensive. The wholesale cost in the developing world in 2014 was to $1.05 wholesale per 20ml vial of medication.

Usage examples of "lidocaine".

The relevance of the find was that the dead man had traces of Lidocaine in him.

After they were done with the electrical defibrillation, the intubation, the epinephrine, the lidocaine and the procainamide, and the chest compressions, they harvested him.

His words slur as if his mouth is numb with lidocaine, and he is almost yelling as he leers at her, checking her out from her hair to her cleavage to her satin cowboy boots.

Then, without further discussion, Baudelio began to inject lidocaine along the margins of his wound.

He put the bag on the gurney, then put a syringe pack and a glass vial of a drug called lidocaine into the bag.

Jasentha was in the emergency room, waiting for the lidocaine to take effect before the doctor on call, a woman, sewed up the long deep gash in her calf.

A bottle of injectible lidocaine and a 3-cc syringe for local anesthesia, plus a few packs of silk and needles.

The thought of having even minor surgery without at least lidocaine sickened her.

You never inject lidocaine directly into the vein in a concentrated form.

She had fallen asleep in bed, and David came into the bedroom, injected the lidocaine, and then pulled her onto the floor, so it would look as if she was trying to reach the door.

Lidocaine, the antiarrhythmic and lo-cal anesthetic, for instance, could cause prolonged seizures if given intravenously in large enough doses.

Brian Dalton, the first of three anesthetists who would work during the six-hour procedure, was administering an axillary block, injecting lidocaine (a novocaine-like drug) deep into the armpit, to dull, during the prepara­tion, sensation in the nerves that ran out to the hand.

They had intravenous fluids, whole blood, crystalloid solutions: both saline and normal serum albumin, morphine sulphate, lidocaine, digitalis preparations.

They had intravenous fluids, whole blood, crystalloid solutions: both saline and normal serum albumin, morphine sulphate, lidocaine, digitalis preparations .