Wikipedia
Langerhans cell
Not to be confused with the cells of the islets of Langerhans, found in the pancreas, or Langhans giant cell.
Langerhans cells are dendritic cells ( antigen-presenting immune cells) of the skin and mucosa, and contain large organelles called Birbeck granules. They are present in all layers of the epidermis except the stratum corneum, which protects against infections, and are most prominent in the stratum spinosum. They also occur in the papillary dermis, particularly around blood vessels, as well as in the mucosa of the mouth, foreskin, and vagina. They can be found in other tissues, such as lymph nodes, particularly in association with the condition Langerhans cell histiocytosis (LCH).