What is "indole"

Indole \In"dole\, Indol \In"dol\([i^]n"d[=o]l), n. [Indigo + -ol of phenol.] (Chem., Physiol. Chem.) A white, crystalline substance, C8H7N, obtained from blue indigo, and almost all indigo derivatives, by a process of reduction; chemically, it is 2,3-benzopyrrole, a bicyclic heterocyclic compound, having a benzene ring fused to a pyrrole ring. It is also formed from proteinaceous matter, together with skatol, by putrefaction, and by fusion with caustic potash, and is present in human excrement, as well as in the intestinal canal of some herbivora. It is produced in rich growth media by the intestinal bacterium Escherichia coli.

n. 1 (context chemistry English) An organic compound, C₈H₇N, found in coal tar, and produced in the gut by the bacterial decomposition of tryptophan; it is an aromatic bicyclic heterocycle having a benzene ring fused with a pyrrole ring; indole and its derivatives occur widely in nature and have many industrial applications. 2 (context chemistry English) Any of the derivatives of indole₁.

Indole is an aromatic heterocyclic organic compound with formula C H N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. Indole is widely distributed in the natural environment and can be produced by a variety of bacteria. As an intercellular signal molecule, indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence. The amino acid tryptophan is an indole derivative and the precursor of the neurotransmitter serotonin.