Longman Dictionary of Contemporary English
n. A room, in a person's home, equipped as an office so that the person may work from home.
The Home Office (HO) is a ministerial department of the Her Majesty's Government of the United Kingdom, responsible for immigration, security, and law and order. As such it is responsible for the police, British Visas and Immigration, and the Security Service (MI5). It is also in charge of government policy on security-related issues such as drugs, counter-terrorism, and ID cards. It was formerly responsible for Her Majesty's Prison Service and Probation Service, but these have transferred to the Ministry of Justice.
It continues to be known, especially in official papers and when referred to in Parliament, as the Home Department.
Usage examples of "home office".
It's a special department in the home office that specializes in making life more complicated for the Guardians.
Ronnie Vallance went behind my back to the Home Office and the Ministry of Health.
The Challis Company's home office is in Terra's capital, and I presume that's where he's fled.
They sat in Honor's home office, and the sliding crystoplast wall of the bay window was open, turning it into a balcony onto the cool spring night.