Douglas Harper's Etymology Dictionary
1707, originally a piece of mandrake root, translation of French maindeglorie, from a corruption of Latin mandragora "mandrake" (see mandrake). The dead man's hand charm is described from mid-15c., but not by this name.
Wikipedia
The Hand of Glory is the dried and pickled hand of a man who has been hanged, often specified as being the left (Latin: sinister) hand, or, if the man were hanged for murder, the hand that "did the deed."
Old European beliefs attribute great powers to a Hand of Glory combined with a candle made from fat from the corpse of the same malefactor who died on the gallows. The candle so made, lighted, and placed (as if in a candlestick) in the Hand of Glory, would have rendered motionless all persons to whom it was presented. The process for preparing the hand and the candle are described in 18th century documents, with certain steps disputed due to difficulty in properly translating phrases from that era. The concept inspired short stories and poems in the 19th century.
Hand of Glory is the tenth, final studio album by Royal Trux. It is composed of recordings made 1985 to 1989 and was released by Drag City in 2002.